HIGHLIGHTS
- who: Camilo Torres and colleagues from the Department of Biochemistry, Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Medical Center, Geert Grooteplein, GA Nijmegen, The Netherlands have published the research: A Computational Investigation of In Vivo Cytosolic Protein Delivery for Cancer Therapy, in the Journal: Pharmaceutics 2021, 13, 562. of /2021/
- what: The authors provide quantitative insights into how enzymatic cargoes can enhance the distribution extent and duration of therapeutic activity already at very low catalytic rates. The authors focused the investigations on solid tumors, while reflecting on the consequences for protein-based therapeutics . . .
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