A computational methodology to screen activities of enzyme variants

HIGHLIGHTS

• who: Enzyme Variants from the Department of Chemistry, University of Copenhagen, Copenhagen, Denmark, Novozymes A/S, Bagsværd, Denmark have published the paper: A Computational Methodology to Screen Activities of Enzyme Variants, in the Journal: PLOS ONE | www.plosone.org of December/17,/2012
• what: The authors develop and test the technique on the Candida Antarctica lipase B (CalB) enzyme. The authors focus on estimating kcat rather than kcat=KM because most industrial uses of enzyme catalysts work at high substrate concentration where kcat is most critical for product formation. While it is possible to . . .
  

   

  

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