HIGHLIGHTS
- who: Michael Jenkyn-Bedford from the (UNIVERSITY) have published the research work: A conserved mechanism for regulating replisome disassembly in eukaryotes, in the Journal: (JOURNAL) of 20/07/2021
- what: Terminated yeast replisome structures To determine the molecular basis for the regulation of CMG ubiquitylation, the authors aimed to solve the structure of a terminated replisome, by adapting the system for reconstituting budding yeast replisomes for structural analysis13. The authors propose that the binding of Dia2LRR and LRR1LRR across the exit channel of the excluded strand reflects convergent evolution, probably indicative of a stringent evolutionary . . .
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