A convenient four-step synthesis of 1-{-[3-(4-methoxy-phenyl)propoxy]-4- methoxyphenethyl}-1h-imidazole hydrochloride as a probing tool for soce assays

HIGHLIGHTS

  • who: Camille D. Dago et al. from the Institut des Sciences Chimiques de Rennes (ISCR), UMR CNRS, groupe CORINT, Desmoulins, Brest , France have published the paper: A Convenient Four-Step Synthesis of 1-{-[3-(4-Methoxy-phenyl)Propoxy]-4- Methoxyphenethyl}-1H-Imidazole Hydrochloride as a Probing Tool for SOCE Assays, in the Journal: (JOURNAL)

SUMMARY

    Variations in cytoplasmic Ca2+ concentration ([Ca2+ ]i ) play an important role in mediating fundamental biological activities for cell proliferation, differentiation, apoptotosis, and gene_expression. The first identified inhibitor of the CRAC (Ca2+ release-activated Ca2+ channel) channel, the archetypal . . .

     

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