A cysteine residue within the kinase domain of zap70 regulates lck activity and proximal tcr signaling

HIGHLIGHTS

  • who: Annika Schultz et al. from the Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany have published the paper: A Cysteine Residue within the Kinase Domain of Zap70 Regulates Lck Activity and Proximal TCR Signaling, in the Journal: Cells 2022, 11, 2723. of 30/08/2022
  • what: To this important finding elucidating the molecular mechanism at the basis of this form of SCID, this work has additionally proposed that C564 is a site of acylation (i.e S-palmitoylation).
  • how: The following primers were designed using the . . .

     

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