A deep-learning-computed cancer score for the identification of human hepatocellular carcinoma area based on a six-colour multiplex immunofluorescence panel

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SUMMARY

An exemplary mIF panel of commonly studied markers for the prognosis of patients with cancers, consisting of four lymphocyte markers, CD3 for T_cells, CD4 for T helper cells, CD8 for cytotoxic T_cells, and FoxP3 for regulatory T_cells, and the checkpoint protein programmed cell death ligand 1 (PD-L1), which is mainly found on immune cells and inhibits T_cell responses, was used. A comparison of the percentage of T_cells and their subsets in the primary tumour (PT) tissues with the adjacent non-tumour liver (NTL) tissues showed that in the PT tissues, T_cells and most . . .

 



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