HIGHLIGHTS
SUMMARY
Based on the analysis of cell differentiation trajectory in scRNA-seq, the authors identified subtypes of HCC cells in the immune micro-environment and searched for prognostic genes associated with cell differentiation. The CIBERSORT algorithm was applied to investigate the infiltration of immune cells in the DRGPI subgroup, and it was found that CD8 T_cells were more enriched in the low DRGPI subgroup, while M0 macrophages were more enriched in the high DRGPI subgroup. Numerous studies have shown that intensive infiltration of CD8 T_cells in the tumor immune microenvironment predicts a good prognosis. Compared . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.