A digital enzyme-linked immunosorbent assay for ultrasensitive measurement of amyloid-β 1-42 peptide in human plasma with utility for studies of alzheimer’s disease therapeutics

HIGHLIGHTS

  • who: Linan Song from the Eli Lilly and Company, Windlesham, UK have published the research: A digital enzyme-linked immunosorbent assay for ultrasensitive measurement of amyloid-β 1-42 peptide in human plasma with utility for studies of Alzheimer’s disease therapeutics, in the Journal: (JOURNAL)
  • what: In the present study, a digital ELISA was developed for measuring plasma Aβ1-42 with improved sensitivity using single molecule array (Simoa) technology with antibodies 3D6 and 21F12, directed at the N- and C-termini of Aβ1-42, respectively. The aims of this study were also to . . .

     

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