A discrete three-amino acid segment (lvi) at the c-terminal end of kinase-impaired erbb3 is required for transactivation of erbb2*

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  • who: Gabriele Schaefer from the (UNIVERSITY) have published the article: A Discrete Three-amino Acid Segment (LVI) at the C-terminal End of Kinase-impaired ErbB3 Is Required for Transactivation of ErbB2*, in the Journal: (JOURNAL)
  • what: The authors designed a series of C-terminal deletion and substitution mutants of ErbB3 and assessed the phosphorylation status of the receptors in the complex. The authors report here that a distinct three-amino_acid segment (LVI) in the intracellular domain of ErbB3 is required for transactivation of ErbB2 and propose that this is an intermediate step between ligand . . .

     

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