A dna vaccine encoding the gn ectodomain of rift valley fever virus protects mice via a humoral response decreased by dec205 targeting

HIGHLIGHTS

• who: Tiphany Chrun from the Research, United States Johns Hopkins University have published the paper: A DNA Vaccine Encoding the Gn Ectodomain of Rift Valley Fever Virus Protects Mice via a Humoral Response Decreased by DEC205 Targeting, in the Journal: (JOURNAL)
• what: The authors evaluated the efficacy of peGn and pscDECeGn in the mouse reference model, and the authors sought to get further insight into the mechanisms underlying the protective immunity. The authors show that the DEC205 targeting of another antigen (mCherry) resulted in a mixed outcome, with an increase of the humoral response and . . .
  

   

  

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