A drug-repositioning screen using splicing-sensitive fluorescent reporters identifies novel modulators of vegf-a splicing with anti-angiogenic properties

HIGHLIGHTS

  • who: Eleanor Star from the (UNIVERSITY) have published the research: A drug-repositioning screen using splicing-sensitive fluorescent reporters identifies novel modulators of VEGF-A splicing with anti-angiogenic properties, in the Journal: (JOURNAL)
  • what: While this reporter has been used and validated by the lab in_vivo in a transgenic mouse model15 for the purpose of this study - to use it in a screen - the authors wanted to pursue more validation in_vitro. Due to one of the goals of this project - to find modulators of angiogenesis with one major target being Oncogenesis tumour angiogenesis - the . . .

     

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