HIGHLIGHTS
SUMMARY
In a previous study, the authors found that the rDNA repeat number evolves from 125 to about 220-250 copies along 160-180 generations in a freshly made ("early") cln3 yeast mutant. In fact, cln3 has a much larger (roughly double) cell volume than the wild_type. The actual number of rDNA repeats in an early mutant is the same as in the parental wild_type and is, therefore, smaller than that needed to maintain the rRNA synthesis rate for such a bigger volume. The free UAF concentration is negligible for a wild_type with 125 repeats . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.