A ferritin-based covid-19 nanoparticle vaccine that elicits robust, durable, broad-spectrum neutralizing antisera in non-human primates

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SUMMARY

    To enable global accessibility, the authors generated a cell line that can enable production of thousands of vaccine doses per liter of cell culture and show that DCFHP-alum maintains potency for at least 14 days at temperatures exceeding standard room temperature. DCFHP formulated with alum is highly immunogenic and stable at elevated temperatures Given the robust immunogenicity of DCFHP formulated with alum and CpG, the authors hypothesized that the use of alum as the sole adjuvant for DCFHP (i.e., DCFHP-alum) might still elicit a robust response. Longer gaps 3 have been . . .

     

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