HIGHLIGHTS
- who: Top from the Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Falmer, Brighton, UK have published the research: A first generation inhibitor of human Greatwall kinase, enabled domain construct, in the Journal: (JOURNAL)
- how: In cellulo efficacy of GKI-1 To more directly address the presence of other offtarget effects and / or any level of compound toxicity the authors conducted a more comprehensive phenotypic analysis of GKI-1 and GWL siRNA (siGWL Figure 5A) treated cells by immunofluorescence (IF) and time-lapse video microscopy.
- future: Clearly more experimental . . .
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