A formylglycine‐peptide for the site‐directed identification of phosphotyrosine‐mimetic fragments**

HIGHLIGHTS

• who: from the (UNIVERSITY) have published the Article: A Formylglycineu2010Peptide for the Siteu2010Directed Identification of Phosphotyrosineu2010Mimetic Fragments**, in the Journal: (JOURNAL)
• what: We have demonstrated the use of formylglycine peptide 3 for site-directed fragment ligation screening.

SUMMARY

The obtained formylglycine peptide 3 was then used to identify phosphotyrosine mimetic fragments F for two PTP, PTP1B and the catalytic domain of SHP2. The GLIDE protoco was used to dock formylglycine peptide 3, hydrate 9, Z-enamines 11 and 12, and the reduced peptides 15, 16, and 18 to the phosphotyrosine peptide . . .

 



If you want to have access to all the content you need to log in!

Thanks :)

Username or Email

Password

Remember me

Lost your password?

If you don't have an account, you can create one here.