HIGHLIGHTS
- who: Julia Vergalli from the University of have published the research: A framework for dissecting affinities of multidrug efflux transporter AcrB to fluoroquinolones, in the Journal: (JOURNAL) of 17/01/2022
- what: The study focused on two isogenic strains: EA27 a wellcharacterized clinical isolate over-expressing AcrAB (the complex formed between the Resistance Nodulation cell Division efflux transporter AcrB and the adaptor protein AcrA) and containing a quinolone resistance-determining regions (QRDR) mutation (see Methods) and EA294 its derivative strain devoid of AcrB. The authors focused on the deep binding pocket of the Tight monomer . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.