A functional genetic screen for metabolic proteins unveils gart and the de novo purine biosynthetic pathway as novel targets for the treatment of luminal a era expressing primary and metastatic invasive ductal carcinoma

HIGHLIGHTS

• who: Manuela Cipolletti from the Universitu00e9 libre de Bruxelles, Belgium Universidad Autou0301noma de la Ciudad de Mu00e9xico, Mexico have published the research: A functional genetic screen for metabolic proteins unveils GART and the de novo purine biosynthetic pathway as novel targets for the treatment of luminal A ERa expressing primary and metastatic invasive ductal carcinoma, in the Journal: (JOURNAL)
• what: The experiments were carried out using the protocol previously described . The aim of this study was to identify metabolic proteins whose inhibition could impede BC cell proliferation by inducing ERa degradation. The findings presented in . . .
  

   

  

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