A functional interaction between liprin-α1 and b56γ regulatory subunit of protein phosphatase 2a supports tumor cell motility

HIGHLIGHTS

• who: Marta Ripamonti from the Division have published the paper: A functional interaction between liprin-u03b11 and B56u03b3 regulatory subunit of protein phosphatase 2A supports tumor cell motility, in the Journal: (JOURNAL) of 14/05/2022
• what: The authors show that this SLiM-mediated interaction guides the binding of liprin-u03b11 to the PP2A holoenzyme. The study has identified the mechanism by which B56u03b3/PP2A is recruited to the edge of migrating tumor cells and shows that the interaction of liprin-u03b11 with B56u03b3 is required for efficient cell spreading and is likely required for . . .
  

   

  

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