A functional loop between yth domain family protein ythdf3 mediated m

HIGHLIGHTS

  • who: Rong Zhou from the Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China have published the paper: A functional loop between YTH domain family protein YTHDF3 mediated m, in the Journal: (JOURNAL) of December/31,/2020
  • what: The authors characterized a functional loop between YTHDF3 and phosphofructokinase PFKL in glycolysis metabolism of HCC. The study demonstrated that YTHDF3 promotes glycolysis by enhancing phosphofructokinase PFKL expression at both mRNA and protein level.
  • how: After 2 weeks the authors used puromycin (MP Biomedicals) to screen stably transfected cells. jetPRIME (Polyplus . . .

     

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