A gene cluster in ginkgo biloba encodes unique multifunctional cytochrome p450s that initiate ginkgolide biosynthesis

HIGHLIGHTS

  • who: Victor Forman from the (UNIVERSITY) have published the article: A gene cluster in Ginkgo biloba encodes unique multifunctional cytochrome P450s that initiate ginkgolide biosynthesis, in the Journal: (JOURNAL) of 15/Oct/2021
  • what: The authors show that five multifunctional cytochrome P450s with atypical catalytic activities generate the tert-butyl group and one of the lactone rings, characteristic of all G. biloba trilactone terpenoids. Combining the BGC findings with transcriptomic data, the authors show that the CYPs located in this BGC have similar expression patterns, not only to GbLPS, but also to an additional CYP . . .

     

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