A genetic association test accounting for skewed x-inactivation with application to biotherapy immunogenicity in patients with autoimmune diseases

HIGHLIGHTS

• who: Philippe Brou00ebt from the University College London, United Kingdom have published the paper: A Genetic Association Test Accounting for Skewed X-Inactivation With Application to Biotherapy Immunogenicity in Patients With Autoimmune Diseases, in the Journal: (JOURNAL)
• what: The authors propose a new score-like test that takes into account for an unknown underlying XCI process with a potentially skewed pattern.
• how: The authors therefore developed a simpler genetic association test accounting for skewed X-inactivation that the authors used to investigate the role of X-linked genetic variants in the occurrence of . . .
  

   

  

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