A global regulatory system links virulence and antibiotic resistance to envelope homeostasis in acinetobacter baumannii

HIGHLIGHTS

  • who: Edward Geisinger et al. from the Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston have published the research: A global regulatory system links virulence and antibiotic resistance to envelope homeostasis in Acinetobacter baumannii, in the Journal: (JOURNAL) of November/27,/2017
  • what: The authors show here that a highly conserved sensory-transduction system BfmRS mediates the coordinate development of both enhanced virulence and resistance in this microorganism. This work shows that BfmRS controls a global regulatory network coupling cellular physiology to the ability to cause invasive drug-resistant infections. The . . .

     

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