A high hepatic uptake of conjugated bile acids promotes colorectal cancer—associated liver metastasis

HIGHLIGHTS

• who: Zongmei Zheng et al. from the Academy of Integrative Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China have published the research work: A High Hepatic Uptake of Conjugated Bile Acids Promotes Colorectal Canceru2014Associated Liver Metastasis, in the Journal: Cells 2021, 10, x FOR PEER REVIEW of /2021/
• what: Collectively, this study revealed that abnormal hepatic BA metabolism, particularly enhanced uptake and thus an excess of TCA in the liver, induces HSC activation and TME formation, thus promoting CRLM.
• how: The Western blot (WB) results found that 24 h of TCA treatment . . .
  

   

  

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