A high-performance liquid chromatography—mass spectrometry method for simultaneous determination of vancomycin, meropenem, and valproate in patients with post-craniotomy infection

HIGHLIGHTS

  • who: Yuting Jin et al. from the Department of Laboratory Medicine, The First Hospital of Jilin University, Changchun, China have published the Article: A High-Performance Liquid Chromatographyu2014Mass Spectrometry Method for Simultaneous Determination of Vancomycin, Meropenem, and Valproate in Patients with Post-Craniotomy Infection, in the Journal: Molecules 2023, 2439 of 22/02/2022
  • what: In this study, an LC-MS/MS method for simultaneous determination of MER, VAN, and VPA in CSF and serum was developed and validated.
  • how: During the optimization of the sample preparation step methanol and acetonitrile were tested . . .

     

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