A high-throughput screen indicates gemcitabine and jak inhibitors may be useful for treating pediatric aml

HIGHLIGHTS

• who: Christina D. Drenberg from the College State University have published the article: A high-throughput screen indicates gemcitabine and JAK inhibitors may be useful for treating pediatric AML, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors report the results of a large-scale screen of human cancer cell lines representing two high-risk subtypes of pediatric AML including MLL rearranged (MLLr) with or without a co-occurring FLT3-internal tandem duplication (FLT3-ITD) mutation and non-Down syndrome acute megakaryoblastic leukemia (AMKL)2-4. The authors evaluate select compounds representing a variety . . .
  

   

  

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