A highly conserved toxo1 haplotype directs resistance to toxoplasmosis and its associated caspase-1 dependent killing of parasite and host macrophage

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  • who: Its d Caspase- and collaborators from the Université Joseph Fourier, CEA, GrenobleEditor: Christopher MSassetti, University of Massachusetts, United States of America have published the Article: A Highly Conserved Toxo1 Haplotype Directs Resistance to Toxoplasmosis and Its Associated Caspase-1 Dependent Killing of Parasite and Host Macrophage, in the Journal: (JOURNAL) of May/13,/2013
  • what: Altogether, the work provide evidence that natural resistance of rat macrophages to T. gondii is a complex trait relying on a mechanism involving the combined activation of at least two pathways: (i) the classical NLRP1a/Caspase-1 pathway, mediating . . .

     

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