A hiv-1 tat mutant protein disrupts hiv-1 rev function by targeting the dead-box rna helicase ddx1

HIGHLIGHTS

  • who: HIV- and collaborators from the QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia Australian Infectious Disease Research Centre, The University of Queensland have published the research work: A HIV-1 Tat mutant protein disrupts HIV-1 Rev function by targeting the DEAD-box RNA helicase DDX1, in the Journal: (JOURNAL)
  • what: The study provides further evidence of an important role for DDX1 in the maintenance of Rev subcellular localization and function. The authors use a Rev-dependent reporter, pGag-RRE, to investigate the roles of identified DEAD-box RNA helicases in Rev function . DDX1 . . .

     

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