A live-attenuated sars-cov-2 vaccine candidate with accessory protein deletions

HIGHLIGHTS

• who: Yang Liu from the Ethics statement Hamster and mouse studies were performed in accordance with the guidance for the Care and Use of Laboratory Animals of the University of Texas Medical Branch (UTMB)The protocol was approved by the Institutional Animal Care and Use Committee (IACUC) at UTMB. The animals were maintained at macroenvironmental temperature and humidity ranges of , to , u00b0F and, % to, %, respectively with a , light/, dark light cycle. All the animal operations were performed under anesthesia by isoflurane to minimize animal suffering. The convalescent sera from , patients (confirmed by the molecular tests with FDA . . .
  

   

  

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