A macrophage membrane-polymer hybrid biomimetic nanoplatform for therapeutic delivery of somatostatin peptide to chronic pancreatitis

HIGHLIGHTS

  • who: Fang Wang and colleagues from the College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, China have published the article: A Macrophage Membrane-Polymer Hybrid Biomimetic Nanoplatform for Therapeutic Delivery of Somatostatin Peptide to Chronic Pancreatitis, in the Journal: Pharmaceutics 2022, 14, 2341. of /2022/
  • what: In this study membranecoated poly(lactic-co-glycolic acid) (PLGA) nanodelivery system was developed to enhance the bioavailability of the somatostatin (SST) peptide which faces the hurdles of short half-life and potential side effects in the treatment of chronic pancreatitis. Taking advantage of the biodegradable PLGA polymer . . .

     

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