A male-specific doublesex isoform reveals an evolutionary pathway of sexual development via distinct alternative splicing mechanisms

HIGHLIGHTS

• who: Caihong Han from the School Southeast University, Nanjing, China have published the paper: A male-specific doublesex isoform reveals an evolutionary pathway of sexual development via distinct alternative splicing mechanisms, in the Journal: (JOURNAL) of 29/06/2022
• what: The authors report that intron retention (IR) generates a male-specific dsx transcript and propose an evolutionary pathway from sexually monomorphic to sex-specific splicing of dsx.
• how: Experimental flies and genetic controls were tested at the same condition and data are collected from at least two independent experiments and are reproducible.
 



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