HIGHLIGHTS
- who: Lisa Donker from the for Molecular Medicine, University Medical Center Utrecht, Universiteitsweg, Utrecht, the Netherlands have published the Article: A mechanical G2 checkpoint controls epithelial cell division through E-cadherin-mediated regulation of Wee1-Cdk1, in the Journal: (JOURNAL) of October/11,/2022
- what: The authors show that epithelial_cells sense changes in cell number through coinciding changes in intercellular forces, which are transduced by E-cadherin adhesions to control a cell-densitydependent G2 checkpoint. An E-cadherin mechanoresponse establishes densitydependent regulation of Wee1 levels Next, the authors aimed to identify the molecular components downstream . . .
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