A metabolic signature to monitor endothelial cell differentiation, activation, and vascular organization

HIGHLIGHTS

• who: Filipa Lopes-Coelho and colleagues from the iNOVA Health, NOVA Medical School have published the research work: A Metabolic Signature to Monitor Endothelial Cell Differentiation, Activation, and Vascular Organization, in the Journal: Biomedicines 2022, 10, x FOR PEER REVIEW of /2022/
• how: As the authors described recently the ALDH inhibition by disulfiram activates monocyte-toendothelial-cell differentiation since ALDH is a stemness marker whose decreased expression and activity is correlated with a progressive differentiation of endothelial progenitor cells to endothelial cells . In this model it was clear that the fatty_acid oxidation and synthesis work . . .
  

   

  

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