A metabolic smorgasbord drives and sustains csc heterogeneity

HIGHLIGHTS

  • who: Michael Kahn from the Department have published the article: A Metabolic Smorgasbord Drives and Sustains CSC Heterogeneity, in the Journal: Cancers 2023, 15, 343. of 16/Dec/2022

SUMMARY

    Cancer stem_cells (CSC) are the major cause of therapy resistance, associated with metastasis and the cause of disease relapse. Normal somatic stem_cells (SSC) and CSC share many common features, thereby complicating the safe elimination of CSC. It is now clear that both normal stem_cells (germ line and somatic) and CSC can sample many different "dishes" at the Smorgasbord table to suit their "behaviors . . .

     

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