A microfluidic approach to rescue als motor neuron degeneration using rapamycin

HIGHLIGHTS

• who: Phaneendra Chennampally from the University of Maine, Orono, ME, USA have published the Article: A microfluidic approach to rescue ALS motor neuron degeneration using rapamycin, in the Journal: Scientific Reports Scientific Reports of 19/03/2021
• what: In this Article mouse embryonic stem_cells possessing the mutant human ALS TDP-43-A315T transgene were successfully derived and differentiated into MNs under both 2D and 3D environments to assess the efficacy of rapamycin as a rescue to the ALS phenotype.

SUMMARY

All MNs were cultured from embryonic stem_cells (ES cells) containing an . . .

 



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