A minimally invasive, lentiviral based method for the rapid and sustained genetic manipulation of renal tubules

HIGHLIGHTS

  • who: Judit Espana-Agusti from the DepartmentUniversity of have published the article: A minimally invasive, lentiviral based method for the rapid and sustained genetic manipulation of renal tubules, in the Journal: Scientific Reports Scientific Reports
  • what: To evaluate the extent of renal lentiviral transduction achieved by the approach , the authors examined multiple sections of both left and right kidneys of injected mice. The authors demonstrate that US-guided intraparenchymal delivery of lentiviral_vectors can induce sustained genetic modification of renal tubular epithelial_cells bypassing the need to engineer novel GEMMs and to breed multiple animals for the . . .

     

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