A mixture of 13 pesticides, contaminants, and food additives below individual noaels produces histopathological and organ weight changes in rats

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  • who: Viorica Dinca from the Animal study Twenty male and , female, week-old Sprague Dawley (CD-SD) rats obtained from the University of Medicine and Pharmacy of Craiova Animal Husbandry were divided into four groups (five males and five females)Animals were acclimatized to laboratory conditions for , weeks before the beginning of the experiment (19, u00b0C room temperature, % humidity, and , h light/dark cycle). Rats were exposed for , months to a mixture of , chemicals in four dose ranges as follows:, u00d7NOAEL (mg/kg BW/day), .0025u00d7NOAEL (mg/kg BW/day), .01u00d7NOAEL (mg/kg BW/day) and, .05xNOAEL . . .

     

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