A model of ipsc-derived macrophages with tnfaip3 overexpression reveals the peculiarities of tnfaip3 protein expression and function in human macrophages

HIGHLIGHTS

  • who: Olga Sheveleva and collaborators from the Laboratory of Cellular and Molecular Basis of Histogenesis, Koltzov Institute of Developmental Biology of have published the Article: A Model of iPSC-Derived Macrophages with TNFAIP3 Overexpression Reveals the Peculiarities of TNFAIP3 Protein Expression and Function in Human Macrophages, in the Journal: (JOURNAL) of 20/Oct/2022
  • what: The model elaborated in study may be used to generate iMacs with a controllable expression of other genes of terest. Similarly, the analysis of the clinical exome of a patient who was a donor of the PBMCs that were used . . .

     

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