HIGHLIGHTS
- who: Peter Sarvari and collaborators from the Department of Bioengineering, Imperial College London, London , BU, UK have published the research: A Modelling Framework Linking Resource-Based Stochastic Translation to the Optimal Design of Synthetic Constructs, in the Journal: Biology 2021, 10, 37. of /2021/
- what: The authors show how the framework can be used to link a synthetic construct's modular design (promoter ribosome binding site (RBS) and codon composition) to protein yield during continuous culture with a particular focus on the effects of low-efficiency codons and their impact on ribosomal queues. Through the . . .
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