A molecular mechanism for transthyretin amyloidogenesis

HIGHLIGHTS

  • who: Ai Woon Yee from the Keele University Laue-Langevin, des Martyrs, , Grenoble, France have published the Article: A molecular mechanism for transthyretin amyloidogenesis, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: As has been tested previously18, experiments carried out at 4 °C in static (non-shaking) conditions provided wellresolved MS spectra, hence these conditions were used for the work described here.

SUMMARY

    Control over the potential energy function used allowed specific residues to be changed into other ones, so that the free_energy change associated with the modifications could be calculated . . .

     

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