A molecular signature of lung-resident cd8+ t cells elicited by subunit vaccination

HIGHLIGHTS

• who: Naveenchandra Suryadevara from the DepartmentVanderbilt University have published the research: A molecular signature of lung-resident CD8+ T cells elicited by subunit vaccination, in the Journal: Scientific Reports Scientific Reports of 29/01/2022
• what: Because OVA-3 lacks the natural u00adCD4+ T_cell epitope-OT-II, and as MPLA adjuvancy requires a functional u00adCD4+ T_cell u00adresponse54, the studies described below were performed using u03b1GC as the adjuvant.
• how: The results are inconsistent with the recent report which showed down regulated Itgal Itga4 and Itgb2 expression consequent to the inhibition of Notch signalling . . .
  

   

  

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