A mouse model of bardet-biedl syndrome has impaired fear memory, which is rescued by lithium treatment

HIGHLIGHTS

• who: Thomas K. Pak and colleagues from the Medical Scientist Training Program, Roy Jand Lucille Carver College of Medicine, University of Iowa have published the research: A mouse model of Bardet-Biedl Syndrome has impaired fear memory, which is rescued by lithium treatment, in the Journal: (JOURNAL) of April/22,/2021
• what: The authors demonstrate that BBS mice have significant impairments in context conditioning a form of associative learning. The authors focused on the use of Bbs1M390R/M390R mice, harboring the most common human BBS mutation, as it recapitulates many of BBS phenotypes present in . . .
  

   

  

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