A mstndel73c mutation with fgf5 knockout sheep by crispr/cas9 promotes skeletal muscle myofiber hyperplasia

HIGHLIGHTS

  • What: In this study, we found that increasing the delivery ratio of Cas9 mRNA to sgRNA can improve the efficiency of the homozygous mutation of the biallelic gene.
  • Who: About eLife`s process and colleagues from the Beijing Key Laboratory for Animal Genetic Improvement, National Engineering Laboratory for Animal Breeding, Technology, China Agricultural University, Beijing, China • Institute of Animal Husbandry and Veterinary have published the research work: A MSTN mutation with FGF5 knockout sheep by CRISPR/Cas9 promotes skeletal muscle myofiber hyperplasia via MEK-ERK-FOSL1 axis, in the Journal: (JOURNAL)
  • How: At . . .

     

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