HIGHLIGHTS
- who: John K. Botson from the AK, USA have published the research work: A multicentre, efficacy and safety study of methotrexate to increase response rates in patients with uncontrolled gout receiving pegloticase (MIRROR): 12-month efficacy, safety, immunogenicity, and pharmacokinetic findings during long-term extension of an open-label study, in the Journal: (JOURNAL) of 17/08/2018
- what: Pegloticase exposures (median observed peak concentration and trough concentration across visits) with methotrexate from this study were compared to the observed values in historical monotherapy phase 3 studies (C0405 and C0406) . Of the 11 patients remaining . . .
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