A multiscale model of complex endothelial cell dynamics in early angiogenesis

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  • who: Daria Stepanova et al. from the Universitat Autònoma de, Bellaterra (Barcelona), Spain, Wolfson Centre for Mathematical, Mathematical Institute, University of Oxford, Oxford, UK, Institució Catalana de Recerca i Estudis have published the article: A multiscale model of complex endothelial cell dynamics in early angiogenesis, in the Journal: (JOURNAL)
  • what: The authors show how externally imposed changes in the extracellular environment (ECM density, VEGF concentration, VEGF gradient) and mutations in gene_expression of ECs can alter the branching pattern of growing sprouts. The authors show that networks created by mutant cells with impaired gene_expression of . . .

     

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