A mutation in vps15 (pik3r4) causes a ciliopathy and affects ift20 release from the cis-golgi

HIGHLIGHTS

  • who: Corinne Stoetzel from the Genetics Laboratory, INSERM, Institute of Medical Genetics of Alsace, University of Strasbourg, Strasbourg Medical School, have published the Article: A mutation in VPS15 (PIK3R4) causes a ciliopathy and affects IFT20 release from the cis-Golgi, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 24/Nov/2016
  • what: Besides being required for trafficking and autophagy the authors show that VPS15 regulates primary cilium length in human fibroblasts as well as ciliary processes in zebrafish. The authors demonstrate its interaction with the golgin GM130 and its localization to the Golgi. The authors . . .

     

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