A nervous system-specific model of creatine transporter deficiency recapitulates the cognitive endophenotype of the disease: a longitudinal study

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  • who: Angelo Molinaro from the (UNIVERSITY) have published the article: A Nervous System-Specific Model of Creatine Transporter Deficiency Recapitulates the Cognitive Endophenotype of the Disease: a Longitudinal Study, in the Journal: (JOURNAL) of 15/Nov/2018
  • what: The authors report that nervous system-specific Cr depletion leads to a progressive cognitive regression starting in the adult age. The authors report a late onset of cognitive decline in nervous system-specific nes-CrT-/y mice, followed by an age-dependent increase of cognitive frailty. In agreement with previous works13-15, the authors report that Cr . . .

     

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