HIGHLIGHTS
- who: NODAL/Activin signalling conditions. and collaborators from the (UNIVERSITY) have published the Article: A network of transcription factors governs the dynamics of NODAL/Activin transcriptional responses, in the Journal: (JOURNAL)
- what: The authors show that binding induces chromatin opening genome wide. The authors determine a mechanism by which induces delayed gene expression by uncovering a self-enabling transcriptional cascade whereby activated SMADs together with induce the expression of Wnt3. The authors show that NODAL/Activin directly induces the expression of Wnt3 via ZIC3 and FOXH1, and that WNT3 then signals via the β-catenin-TCF . . .
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