A new ampk isoform mediates glucose-restriction induced longevity non-cell autonomously by promoting membrane fluidity

HIGHLIGHTS

• who: Jin-Hyuck Jeong from the (UNIVERSITY) have published the paper: A new AMPK isoform mediates glucose-restriction induced longevity non-cell autonomously by promoting membrane fluidity, in the Journal: (JOURNAL) of 23/06/2021
• what: Using 1H-NMR metabolite analyses and inter-species genetics, the authors demonstrate that E. coli mutants depleted of intracellular glucose extend C. elegans lifespans, serving as bona fide glucose-restricted (GR) diets. The authors provide the molecular mechanisms by which organisms respond to GR condition to promote longevity using conserved factors across species. Although the authors show that glucose . . .
  

   

  

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