A new challenge for the old excipient calcium carbonate: to improve the dissolution rate of poorly soluble drugs

HIGHLIGHTS

  • who: Valeria Ambrogi from the (UNIVERSITY) have published the research work: A New Challenge for the Old Excipient Calcium Carbonate: To Improve the Dissolution Rate of Poorly Soluble Drugs, in the Journal: Pharmaceutics 2023, 15, 300. of /2023/
  • what: In this paper the effects of the presence of insoluble additives such as CaCO3 on drug solubilization was studied. This research showed that mesoporous CaCO3 can prevent celecoxib recrystallization in a lack of humidity where the conversion of vaterite into calcite is slower.
  • future: Studies are required to strongly support the findings described here . . .

     

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