A new generation of ultrasmall nanoparticles inducing sensitization to irradiation and copper depletion to overcome radioresistant and invasive cancers

HIGHLIGHTS

  • who: Paul Rocchi and collaborators from the Institut Lumiu00e8re Matiu00e8re, Universitu00e9 Claude Bernard Lyon CNRS, Villeurbanne, France have published the research work: A New Generation of Ultrasmall Nanoparticles Inducing Sensitization to Irradiation and Copper Depletion to Overcome Radioresistant and Invasive Cancers, in the Journal: Pharmaceutics 2022, 14, 814. of /2022/
  • what: The aim of this study was to develop a multimodal ultrasmall nanoparticle CuPRiX based on the clinical AGuIX nanoparticle made of the polysiloxane matrix on which gadolinium chelates are grafted. After showing the ability of CuPRiX to decrease cell migration and invasion with a . . .

     

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